Results from a large, national clinical trial show that corneal donor tissue can be safely stored for 11 days without negatively impacting the success of transplantation surgery to restore vision in people with diseases of the cornea. The cornea is the eye's clear outer covering. Currently, donor corneas are generally not used for surgery in the United States if they have been preserved for longer than seven days. Two reports from the Cornea Preservation Time Study (CPTS), which was funded by the National Eye Institute, part of the National Institutes of Health, appear online November 10 in JAMA Ophthalmology.

River blindness, or onchocerciasis, is a disease caused by a parasitic worm found primarily in Africa. The worm (Onchocerca volvulus) is transmitted to humans as immature larvae through bites of infected black flies. Symptoms of infection include intense itching and skin nodules. Left untreated, infections in the eye can cause vision impairment that leads to blindness. Mass distribution of ivermectin is currently used to treat onchocerciasis. However, this treatment can be fatal when a person has high blood levels of another filarial worm, Loa loa.

In his lab at Boston University, Darren Roblyer, PhD, studies mice, invents new medical devices, and guides a clinical trial for women getting chemotherapy as their first treatment for breast cancer. All 3 of these projects are funded by his grant from the American Cancer Society. They all also have the same goal: To learn how well chemotherapy is working to destroy a tumor, as quickly as possible after the treatment is started.

The American College of Surgeons National Surgical Quality Improvement Program has recognized the Mayo Clinic Hospitals in Rochester and Arizona for achieving meritorious outcomes for surgical patient care.  As a program participant, Mayo tracks the outcomes of inpatient and outpatient surgical procedures in order to inform and direct quality improvement efforts.

Mayo Clinic will have the first clinical 7-Tesla MRI scanner in North America that has been cleared by the U.S. Food and Drug Administration (FDA). This MRI scanner, the MAGNETOM Terra, will be operational at Mayo Clinic later in 2017. The manufacturer, Siemens Healthineers, received FDA clearance on October 12 for clinical use of the scanner to image the head and knee.

In the first study of its kind, an international team of genomics researchers has identified new regions of the human genome that are associated with skin color variation in some African populations, opening new avenues for research on skin diseases and cancer in all populations. These findings may help researchers determine if humans with certain DNA sequences are more or less susceptible to DNA damage caused by ultraviolet radiation (UVR) or respond to cellular stress differently. National Institutes of Health researchers contributed to this effort, led by Sarah Tishkoff, Ph.D., at the University of Pennsylvania in Philadelphia. The findings were published October 12, 2017, in the journal Science.