The National Institutes of Health's High-Risk, High-Reward Research program, part of the NIH Common Fund, funded 86 awards to exceptionally creative scientists proposing to use highly innovative approaches to tackle major challenges in biomedical research. The program supports high-risk ideas with high-impact potential, such as recording the history of an individual cell in its DNA for future playback; understanding how bacteria in the microbiome can share anti-drug-resistance genes among themselves; resetting the immune system to allow universal organ transplants; and reimagining clinical trials to make them more personalized and more effective.

Obsessive-compulsive disorder (OCD) features a pattern of unreasonable thoughts and fears (obsessions) that lead you to do repetitive behaviors (compulsions). These obsessions and compulsions interfere with daily activities and cause significant distress.

Rochester, Minnesota - Can drinking coffee help you live longer? Two studies report that it may be true. Both studies, published in Annals of Internal Medicine, show drinking coffee likely benefits your health. One study found coffee drinking is associated with a reduced risk of death from various diseases, and the other study showed drinking a lot of coffee is associated with a lower death risk in African-Americans, Japanese-Americans, Latinos and Caucasians.

Rochester, Minnesota - In a new study published in Prosthetics and Orthotics International, Mayo Clinic researchers describe the direct medical costs of falls in adults with a transfemoral amputation. In this type of amputation, the leg is amputated above the knee. This work provides a comparison for policymakers when evaluating the value of more expensive technologies, say the authors.

Washington, DC - Today, Health and Human Services Secretary Tom Price, M.D., named Brenda Fitzgerald, M.D., as the 17th Director of the Centers for Disease Control and Prevention (CDC) and Administrator of the Agency for Toxic Substances and Disease Registry (ATSDR).